Neogene Therapeutics is a pre-clinical stage biotechnology company aiming to change the paradigm of treatment for solid cancers. Our mission is to provide cancer patients with T cell therapies targeting mutated proteins called neo-antigens, which are present on cancer cells as a consequence of DNA mutations. Neogene is developing novel technologies to enable the engineering of ‘designer T cells’ with neo-antigen specificities that display an optimized ability to seek and destroy cancer cells.
We are seeking a highly motivated individual with an affinity for (molecular) biology or immunology to support our R&D bioinformatics team as a Junior Bioinformatician. The individual will help further develop our neoantigen-based T cell therapy pipeline and will support ongoing bioinformatic analyses.
Responsibilities include, but are not limited to:
Collaborate with the R&D team to support the analysis of experimental research aiming to develop novel technologies to enable neo-antigen based T cell therapies.
Support the TCR selection facility to analyze patient screens for identification, characterization and selection of personalized neo-antigen specific TCRs.
Support the development of new tools to be used in our neoantigen-based TCR discovery platform.
Implement and test analysis pipeline innovations.
Presentation of obtained results in internal work discussions.
Other duties as assigned.
M.Sc. in Bioinformatics or a closely related field.
Experience with either R or Python and Bash is required. Competencies in additional (scripting) languages are a plus.
Affinity with (molecular) biology and/or immunology is a plus.
Hands-on experience with the analysis and interpretation of large scale NGS data sets by common next-generation sequencing platforms (Illumina, Pacific Bio and Oxford Nanopore) is a plus.
Experience with Dockers is a plus.
A strong sense of urgency with regards to work duties and the ability to deliver results based on challenging timelines.
Strong verbal and written communication skills and the ability to communicate results to a diverse cross-functional audience.
We are seeking a highly-motivated team player with strong interpersonal skills. We offer the opportunity to join a highly dynamic growth-stage biotech company. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value pro-active team-players who pursue their goals with dedication, endurance and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide a unique opportunity to be a major contributor to the success of a well-positioned, well-financed growth-stage biotechnology company.
If you are interested please submit your electronic application including cover letter and CV to firstname.lastname@example.org